1. Begin by cooking the macaroni according to the package instructions. Drain the cooked pasta and set it aside to cool slightly.

2. In a large bowl, combine the cooked macaroni, shredded cheddar cheese, softened cream cheese, and crumbled bacon. Mix these ingredients together until they are well incorporated.

3. Divide the beef into 8 equal portions and gently form them into evenly-sized patties, creating a small indentation in the center of 4 of the patties.

4. Carefully spoon the prepared mac and cheese mixture into the indentations of the 4 patties and top each with one of the remaining 4 plain patties, sealing the edges tightly.

5. Sprinkle the patties generously with garlic powder, onion powder, salt, and black pepper.

6. Grill or pan-fry the burgers over medium heat for 6 to 8 minutes per side, until they reach your desired level of doneness.

7. Assemble each burger on a toasted bun and top with lettuce, tomato, or any other desired toppings.

8. Serve hot and enjoy the ooey-gooey, bacon-y goodness.